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KMID : 0382320060260010025
Environmental Mutagens and Carcinogens
2006 Volume.26 No. 1 p.25 ~ p.29
Purification of a Antimicrobial Peptide from the Marine Mussel, Mytilus coruscus
Kim In-Hae

Kim Jin-Uk
Lee Jae-Hwa
Abstract
Antimicrobial peptides (AMPs) play an important role in this response by rapidly killing invading microorganisms. In this study antimicrobial peptide has been isolated from acidified whole body extract of a bivalve mollusk, the marine mussel (Mytilus coruscus). This peptide purified to homogeneity by gel-filtration and reversed-phase high performance liquid chromatography. The molecular weight was 1464.92 Da, determined by MALDI-TOF Mass spectrometry. In addition to growth inhibition of Escherichia coli D31.
KEYWORD
AMPs, Marine mussel, MALDI-TOF Mass
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