KMID : 0382320060260010025
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Environmental Mutagens and Carcinogens 2006 Volume.26 No. 1 p.25 ~ p.29
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Purification of a Antimicrobial Peptide from the Marine Mussel, Mytilus coruscus
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Kim In-Hae
Kim Jin-Uk Lee Jae-Hwa
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Abstract
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Antimicrobial peptides (AMPs) play an important role in this response by rapidly killing invading microorganisms. In this study antimicrobial peptide has been isolated from acidified whole body extract of a bivalve mollusk, the marine mussel (Mytilus coruscus). This peptide purified to homogeneity by gel-filtration and reversed-phase high performance liquid chromatography. The molecular weight was 1464.92 Da, determined by MALDI-TOF Mass spectrometry. In addition to growth inhibition of Escherichia coli D31.
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KEYWORD
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AMPs, Marine mussel, MALDI-TOF Mass
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